San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in primetime on Sunday.

Here's where every NFL team stands in both conferences in the race to make the playoffs after the Thursday and Friday games ...

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium in Orchard Park, New York, on Sunday, December 1, at ...

The Bills are 9-2, their best start since 1992, and with a win would clinch their fifth straight AFC East title.

The Bills welcome the 49ers to upstate New York on Sunday Night Football in Week 13. Buffalo (9-2) continues its quest to ...

According to ESPN's Adam Schefter, San Francisco 49ers quarterback Brock Purdy (shoulder) is anticipated to play in Sunday ...